Edta Trisodium

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• EDTA is used in chelation therapy for acute hypercalcemia, mercury poisoning and lead poisoning^[7].


• Combined with chromium, EDTA is used to evaluate kidney function. It is administered intravenously and its filtration into the urine is monitored. This method is considered the gold standard for evaluating glomerular filtration rate, Cr-EDTA's sole way out of the body is via glomerular filtration as it is not secreted or metabolised in any other way.


• Used as anticoagulant for blood samples


• In veterinary ophthalmology EDTA may be used as an anticollagenase to prevent the worsening of corneal ulcers in animals.


• Some laboratory studies also suggest that EDTA chelation may prevent collection of platelets ([or plaque] which can otherwise lead to formation of blood clots and prevent blood flow) on the walls of blood vessels [such as arteries]. These ideas are theoretical, however a major clinical study of the effects of EDTA on coronary arteries is currently (2008) proceeding ^{[8] [3]}?


• Dentistry as a root canal irrigant to remove inorganic debris (smear layer) and prepare root canals for obturation.